A full closure of the M1 is in place between junction 10 and 12 after a road traffic collision.
At least one person is known to have been injured and requires rescuing by air ambulance.
A Beds Police spokesman said: “We were called at 12.39pm to reports of a two vehicle road traffic collision on the M1 northbound between junctions 10 and 11.
“Officers remain on the scene, where there is a full road closure in place for the air ambulance. Ambulance and fire services are also in attendance and it is believed one person is injured.”
An East of England Ambulance spokesman confirmed that a man in his 50s was flown to Addenbrookes Hospital with suspected leg and abdominal injuries.
In addition, there was also a broken down lorry on the southbound carriageway between junctions 12 and 11.