More than 1,000 heartfelt letters pleading for a rethink on the shake up of hospital services will be delivered to Downing Street tomorrow (Wednesday).
The giant bundle, collected during last November's Big No rally in Hemel Hempstead, will be handed over by the town's MP Mike Penning.
Hundreds of people penned letters to Prime Minister Gordon Brown during the campaign, begging him to step in ov
er changes to the town's NHS services.
More were collected during the months that followed in special post boxes across Dacorum and supporters have vowed to take every one to London.
Big No organiser Jan Maddern, of Swan Mead, Hemel Hempstead, will be among them.
She said: "We've been fighting for so many years and the letters were a chance for people to explain what it meant to them personally.
"It's easy for anyone to sign on the dotted line in a petition, but to sit and put pen to paper takes more than that and was so important for people to do.
"It gives an idea of the impact this will have on each individual person."
Hemel Hempstead's A&E is due for closure and will be replaced with an urgent care centre, an out-of-hours GP service and a GP-led health centre.
Cases of serious illness and injury will be sent to casualty in Watford.